FAM111B Polyclonal Antibody, 20ul Cell Dissociation Overexpression of this gene product
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FAM111B Polyclonal Antibody, 20ul Cell Dissociation Overexpression of this gene productFAM111B encodes a protein with a trypsin like cysteine serine peptidase domain in the C terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog
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