TOP1M Polyclonal Antibody, 100ul Filtration but our experiment always detected

but our experiment always detected a 60-70kDa protein by western blot

Multiple alleles of this gene exhibiting variations in the length of the tandem repeats| polymorphic cleavage sites and polymorphic stop codons have been identified

This protein is an outward-rectifying

Belongs to the protein phosphatase inhibitor 1 family

Overexpression of this gene has been implicated in tumorigenesis

TOP1M Polyclonal Antibody, 100ul Filtration but our experiment always detectedThis gene encodes a mitochondrial DNA topoisomerase that plays a role in the modification of DNA topology. The encoded protein is a type IB topoisomerase and catalyzes the transient breaking and rejoining of DNA to relieve tension and DNA supercoiling generated in the mitochondrial genome during replication and transcription. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.