TRIPC Polyclonal Antibody, 100ul Dry Bath CCKAR (cholecystokinin A receptor) encodes

CCKAR (cholecystokinin A receptor) encodes a G-protein coupled receptor that binds non-sulfated members of the cholecystokinin (CCK) family of peptide hormones

and a proline-rich region containing binding sites for SH3 domains

This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor

The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling

Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP

TRIPC Polyclonal Antibody, 100ul Dry Bath CCKAR (cholecystokinin A receptor) encodesComponent of PA700, an ATP dependent multisubunit protein that activates the proteolytic activities of the multifunctional proteinase (20S proteasome) of the 26S complex. Specifically interacts with the ligand binding domain of the thyroid hormone receptor (in a thyroid hormone T3 independent manner) and with retinoid X receptor (RXR). Could be E3 ubiquitin protein ligase which accepts ubiquitin from an E2 ubiquitin conjugating enzyme in the form of a