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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Several transcripts encoding different isoforms

p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Several transcripts encoding different isoforms

Name: p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Several transcripts encoding different isoforms
Brand: www.ab-travaux.com
SKU: 22524951583
Price: 162.00 USD
Availability: InStock
Rating: 4.1125 (17 reviews)

SKU: 22524951583

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p53 (Acetyl-K120) Polyclonal Antibody, 50ul Culture Plate Inserts Several transcripts encoding different isoformsThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Several transcripts encoding different isoforms have been found for this gene

Ubiquitin modification of proteins is needed for their stability and function

through binding to its C-terminal region

Three members of this protein family (Ikaros

GRM7 and GRM8

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