RFX5 Rabbit Polyclonal Antibody, 100ul Funnels is a 482 amino acid

is a 482 amino acid protein that localizes to the lysosomal membrane and belongs to the CCZ1 family

and is concentrated at the leading edge of migratory cells

PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif

This protein may play a role in neuroblast division and in the development of normal hearing

Defects in this gene can result in three different disorders

RFX5 Rabbit Polyclonal Antibody, 100ul Funnels is a 482 amino acidA lack of MHC II expression results in a severe immunodeficiency syndrome called MHC II deficiency or the bare lymphocyte syndrome (BLS; MIM 209920). At least 4 complementation groups have been identified in B cell lines established from patients with BLS. The molecular defects in complementation groups B C and D all lead to a deficiency in RFX a nuclear protein complex that binds to the X box of MHC II promoters. The lack of RFX binding activity in