AMPD2 Polyclonal Antibody, 100ul Peptide Synthesis Catalytic activity:Exonucleolytic cleavage in the

Catalytic activity:Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates

involved in leukocyte transmigration

APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome

Seems to negatively regulate apoptosis by promoting FADD phosphorylation

SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs

AMPD2 Polyclonal Antibody, 100ul Peptide Synthesis Catalytic activity:Exonucleolytic cleavage in theAdenosine monophosphate deaminase 2 encoded by AMPD2 is important in purine metabolism by converting AMP to IMP. The encoded protein, which acts as a homotetramer, is one of three AMP deaminases found in mammals. Several transcript variants encoding different isoforms have been found for AMPD2.