MEK-2 Polyclonal Antibody, 50ul[BT-AP11254] Peripheral Blood Separation Tube Overexpression confers antiestrogen resistance on

Overexpression confers antiestrogen resistance on breast cancer cells

This process is known as cotranslational processing

Cleavage of the alpha chain by a convertase enzyme results in the formation of the C5a anaphylatoxin

RAD23 homolog B

Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam

MEK-2 Polyclonal Antibody, 50ul[BT-AP11254] Peripheral Blood Separation Tube Overexpression confers antiestrogen resistance onThe protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1 ERK2 and MAPK2 ERK3. The activation of this kinase itself is dependent on the Ser Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC