GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation The alpha and alpha' chains

The alpha and alpha' chains contain the catalytic site

Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function

This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I)

members of which have been identified in many animal species ranging from the nematode to human

Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites

GNAO Polyclonal Antibody, 20ul Drug Development and Evaluation The alpha and alpha' chainsThe protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G protein signal transducing complex. Defects in this gene are a cause of early onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.