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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels are membrane-bound proteins with long

SKU: 24381194506

4.3
PLN123.75 PLN169.75

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Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels are membrane-bound proteins with longThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

are membrane-bound proteins with long N termini containing multiple domains

generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling

which suggested its role in the TGF beta induced growth inhibition

COL4A3 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter

The protein (BCL2 like 11) encoded by BCL2L11 belongs to the BCL-2 protein family

Rb Polyclonal Antibody, 100ul[BT-AP07686] Vessels are membrane-bound proteins with longThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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