E-cadherin Monoclonal Antibody, 100ul[BT-MCA0453] Peptide Library The encoded protein is necessary

The encoded protein is necessary for p53-mediated caspase activation and apoptosis

This calpain protein appears to have protease activity and calcium-binding ability

Allelic variants are associated with prostate and brain cancer susceptibility

Inhibits SUV39H1 methyltransferase activity

Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD

E-cadherin Monoclonal Antibody, 100ul[BT-MCA0453] Peptide Library The encoded protein is necessaryThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated