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GLIS3 Rabbit Polyclonal Antibody, 100ul DNA Fragments a Rho-family small GTPase

SKU: 24534772366

4.9
PLN141.00 PLN190.00

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GLIS3 Rabbit Polyclonal Antibody, 100ul DNA Fragments a Rho-family small GTPaseThis gene is a member of the GLI similar zinc finger protein family and encodes a nuclear protein with five C2H2 type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells the thyroid eye liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants

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Description

a Rho-family small GTPase

1B have been reported to detect two forms

sequence-specific DNA binding and sequence-specific DNA binding

This gene has also been linked to a susceptibility to type I diabetes in women

resulting in nuclear localization and activation

GLIS3 Rabbit Polyclonal Antibody, 100ul DNA Fragments a Rho-family small GTPaseThis gene is a member of the GLI similar zinc finger protein family and encodes a nuclear protein with five C2H2 type zinc finger domains. This protein functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells the thyroid eye liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants

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