EXOC4 Rabbit Polyclonal Antibody, 20ul Funnels Allelic variants of this gene

Allelic variants of this gene are associated with the autosomal-recessive disorder Joubert syndrome

May act as a motor required for the retrograde RAB7 regulated transport of Golgi membranes and associated vesicles along microtubules

suggesting either heavy glycosylation or dimerization

Two transcript variants

Mutations in this gene are associated with type II Stickler syndrome and with Marshall syndrome

EXOC4 Rabbit Polyclonal Antibody, 20ul Funnels Allelic variants of this geneThe protein encoded by this gene is a component of the exocyst complex a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex including this protein are found to interact with the