TAB3 Polyclonal Antibody, 20ul ssDNA Synthesis It mediates cAMP-gene regulation by

It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein

which may function as a transcription factor

This gene is located at the junction of certain disease-related chromosomal translocations

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The protein encoded by PRKCE (protein kinase C epsilon)is one of the PKC family members

TAB3 Polyclonal Antibody, 20ul ssDNA Synthesis It mediates cAMP-gene regulation byThe product of this gene functions in the NF kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2 TAB2, forms a ternary complex with the protein kinase MAP3K7 TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro inflammatory cytokines TNF or IL 1. Subsequent MAP3K7 TAK1 kinase activity triggers a signaling cascade leading to activation of the NF kappaB transcription