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LIMK-2(Phospho Thr505) Polyclonal Antibody, 50ul Liquid Handling &Storage The C-terminus contains binding sites

SKU: 25339577170

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LIMK-2(Phospho Thr505) Polyclonal Antibody, 50ul Liquid Handling &Storage The C-terminus contains binding sitesThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

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Description

The C-terminus contains binding sites for proteins such as beta-1-integrin| actin| and vinculin

TSC22D1 (TSC22 domain family member 1) encodes a member of the TSC22 domain family of leucine zipper transcription factors

an adenylyl cyclase

but through transcription factors MEF2C and MEF2D

skeletal muscle and kidney and

LIMK-2(Phospho Thr505) Polyclonal Antibody, 50ul Liquid Handling &Storage The C-terminus contains binding sitesThere are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein protein interactions. LIM kinase 1 and LIM kinase 2 belong to a small subfamily with a unique combination of 2 N terminal LIM motifs and a C terminal protein kinase

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