TSP50 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Two pseudogenes of this gene

Two pseudogenes of this gene are located on the long arm of chromosome 17

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TIE1

and it is located in a cluster with three other family members on chromosome 7

Aberrant expression of this gene may paly a role in tumorigenesis

through binding to its C-terminal region

TSP50 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Two pseudogenes of this geneAlthough related to peptidase S1 family, lacks the conserved active Ser residue in position 310 which is replaced by a Thr, suggesting that it has no protease activity.,miscellaneous: DNA hypomethylation is accompanied by the expression of the gene in the testis.,Belongs to the peptidase S1 family.,Contains 1 peptidase S1 domain.,tissue specificity: Testis specific. Differentially expressed in some breast cancer tissues.,