IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 50ul Funnels a Rho-family small GTPase

a Rho-family small GTPase

The encoded protein is a member of the alpha family of G proteins

It is an essential component of the transcription factor TFIIH

The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance

Interacts with the N-terminal part of PRKCI and PRKCZ

IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 50ul Funnels a Rho-family small GTPaseThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.