PHF3 Polyclonal Antibody, 50ul Antibody Humanization May be involved in Ca(2+)-dependent

May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis

Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency

2007 [PubMed 17353262])

and loss of function of CTPS1 has been associated with immunodeficiency

which suggested that TNFAIP2 may be a retinoic acid target gene in acute promyelocytic leukemia

PHF3 Polyclonal Antibody, 50ul Antibody Humanization May be involved in Ca(2+)-dependentPHF3 encodes a member of a PHD finger containing gene family. PHF3 may function as a transcription factor and may be involved in glioblastomas development. Alternative splicing results in multiple transcript variants.