BCL3 Polyclonal Antibody, 100ul Cell Biology This gene is localized to

This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers

and the truncated form additionally interacts with CCR1 and CCR2

Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival

Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness

and the adenovirus E1A-associated cellular p300 transcriptional co-activator protein

BCL3 Polyclonal Antibody, 100ul Cell Biology This gene is localized toThis gene is a proto oncogene candidate. It is identified by its translocation into the immunoglobulin alpha locus in some cases of B cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co activator that activates through its association with NF kappa B homodimers. The expression of this gene can be induced by NF