CDC42 Polyclonal Antibody, 20ul Cell fragmentation and collection The encoded protein is found

The encoded protein is found to be associated with centromeres of mitotic HeLa cells| which suggests that this protein is a functional homolog of yeast Nuf2

or heterodimer with apolipoprotein D

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but not BRCA1

PPP4C-PPP4R2

CDC42 Polyclonal Antibody, 20ul Cell fragmentation and collection The encoded protein is foundThe protein encoded by this gene is a small GTPase of the Rho subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42 1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein.