CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries The primary function of the

The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS

The long non-coding RNA transcripts interact with a variety of proteins

thus| it functions as a regulator of a wide variety of downstream proteins| including tumor suppressor proteins p53 and BRCA1| checkpoint kinase CHK2| checkpoint proteins RAD17 and RAD9| and DNA repair protein NBS1

This gene is expressed in both normal and tumor cells

Similar genes in zebrafish and mouse have been shown to regulate the transcription of genes that control the production of motile cilia

CD6 Polyclonal Antibody, 100ul[BT-AP01522] Human Genome Knockout Libraries The primary function of theCD6 (CD6 molecule) encodes a protein found on the outer membrane of T lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. CD6 product is important for continuation of T cell activation. CD6 may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants