ALDH1A1 Monoclonal Antibody, 50ul Immune Cell Preparation mediator complex subunit 12 (MED12)

mediator complex subunit 12 (MED12)

Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

and in resulting in poor coordination of speech and body movements

consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC

which has a low Km for acetaldehydes

ALDH1A1 Monoclonal Antibody, 50ul Immune Cell Preparation mediator complex subunit 12 (MED12)The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes