FA11 Rabbit Polyclonal Antibody, 50ul[BT-AP09940] Insect Expression Mutations in LMNA lead to

Mutations in LMNA lead to several diseases: emery-Dreifuss muscular dystrophy

Plays an essential role in the survival of diffuse-type gastric cancer cells

excellent resistance to chemical corrosion and to high temperatures and pressure

This gene encodes the human homolog of yeast class C Vps18 protein

metabolic control

FA11 Rabbit Polyclonal Antibody, 50ul[BT-AP09940] Insect Expression Mutations in LMNA lead toThis gene encodes coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains resulting in activated factor XIa a serine protease