SSRG Polyclonal Antibody, 50ul Peptide Library Expansion of a 20 amino

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

One of several members of the Ser/Thr protein kinase family

six B-chains

It is expressed at low levels in the cytoplasm of pro-B and pre-B cells and present on the cell surface only at mature stages of B-cell differentiation

Mutations in this gene are the cause of X-linked lymphoproliferative syndrome

SSRG Polyclonal Antibody, 50ul Peptide Library Expansion of a 20 aminoThe signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR is comprised of four membrane proteins subunits: alpha, beta, gamma, and delta. The first two are glycosylated subunits and the latter two are non glycosylated subunits. This gene encodes the gamma subunit, which is predicted to span the membrane four times.