PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Isoform 4 is expressed in
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PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos Isoform 4 is expressed inThe protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic
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