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PDGF-D Polyclonal Antibody, 100ul Biomatrix is the most cytotoxic and

SKU: 28965675964

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PDGF-D Polyclonal Antibody, 100ul Biomatrix is the most cytotoxic andPlatelet derived growth factor D encoded by PDGFD is a member of the platelet derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this

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Description

is the most cytotoxic and is generally only transiently expressed during apoptosis

This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions

The protein encoded by this intronless gene is found in the nucleus| where it can inhibit DNA synthesis and promote S phase arrest coupled to apoptosis

Pseudogenes of this gene are present on chromosomes 4 and 17

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

PDGF-D Polyclonal Antibody, 100ul Biomatrix is the most cytotoxic andPlatelet derived growth factor D encoded by PDGFD is a member of the platelet derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this

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