Chk2(Phospho-Ser19) Rabbit Polyclonal Antibody, 20ul Enzymes & Activity Assays The phenotype of malignant melanomas
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Chk2(Phospho-Ser19) Rabbit Polyclonal Antibody, 20ul Enzymes & Activity Assays The phenotype of malignant melanomasIn response to DNA damage and replication blocks cell cycle progression is halted through the control of critical cell cycle regulators. The protein encoded by this gene is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated the
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