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DNA2 Polyclonal Antibody, 20ul Peptide Modification DRD4 contains a polymorphic number

SKU: 29881499537

4.3
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DNA2 Polyclonal Antibody, 20ul Peptide Modification DRD4 contains a polymorphic numberThis gene encodes a member of the DNA2 NAM7 helicase family. The encoded protein is a conserved helicase nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia 6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

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Description

DRD4 contains a polymorphic number (2-10 copies) of tandem 48 nt repeats

Interacts with ATAD2 and this interaction is enhanced by estradiol

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

|Contains 1 Ig-like (immunoglobulin-like) domain

MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins

DNA2 Polyclonal Antibody, 20ul Peptide Modification DRD4 contains a polymorphic numberThis gene encodes a member of the DNA2 NAM7 helicase family. The encoded protein is a conserved helicase nuclease involved in the maintenance of mitochondrial and nuclear DNA stability. Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia 6 (PEOA6) and Seckel syndrome 8. Alternatively spliced transcript variants have been found for this gene.

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