UBA6 Polyclonal Antibody, 100ul Biochemical Reagents Mutations in this gene cause

Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP)

which is a subunit of the nuclear pore complex that functions in active transport of proteins

Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes

|tissue specificity:Ubiquitous

Polymorphisms in this gene are associated with systemic lupus erythematosus and allergic rhinitis

UBA6 Polyclonal Antibody, 100ul Biochemical Reagents Mutations in this gene causeModification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin like proteins controls many signaling networks and requires a ubiquitin activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin like proteins (Jin et al., 2007