Rat Insulin-like Growth Factor Binding Protein 6, IGFBP-6 ELISA Kit, 96T Low-speed Centrifuges Nuclear functions are attributed to

Nuclear functions are attributed to fully reduced HGMB1

in complex with its regulatory protein SAV1

it may function in fertility

Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling

Members of this family encode proteins that play a role in the biogenesis of autophagosomes

Rat Insulin-like Growth Factor Binding Protein 6, IGFBP-6 ELISA Kit, 96T Low-speed Centrifuges Nuclear functions are attributed toIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration.