UVRAG Polyclonal Antibody, 50ul Organelle Studies This protein is a cytosolic

This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH

Upregulation of this gene has been associated with hepatocellular carcinomas

GO annotations related to this gene include nucleotide binding and calmodulin binding

It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion

vasoconstriction

UVRAG Polyclonal Antibody, 50ul Organelle Studies This protein is a cytosolicThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.