ANTR2 Polyclonal Antibody, 20ul Site-directed Mutagenesis Its encoded protein is secreted

Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers

DGC forms a link between the F-actin cytoskeleton and the extracellular matrix

These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD

Zinc finger E-box-binding homeobox 2 encoded by ZEB2 is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins

The protein localizes to the plasma membrane and pericentrosomal vesicles

ANTR2 Polyclonal Antibody, 20ul Site-directed Mutagenesis Its encoded protein is secretedThis gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.