p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments Potent coactivator of PGC1alpha and

Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells

It also interacts with other transcription factors

Paired box transcription factors are important regulators in early development

CLCC1 is expressed as four isoforms due to alternative splicing events

Reduced expression of this protein has been implicated in cardiomyopathies

p27(Phospho Ser178) Polyclonal Antibody, 20ul DNA Fragments Potent coactivator of PGC1alpha andThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from