Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing CERKL was initially identified as

CERKL was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease

Alternative sp

RAD17 checkpoint clamp loader component binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage

An important paralog of this gene is ABHD12

and they may be partners in a common signaling cascade involved in tubular morphogenesis

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00859] Microbial Genome Editing CERKL was initially identified asBCL2 (BCL2, apoptosis regulator) encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.