Smad3 Polyclonal Antibody, 50ul[BT-AP14308] Cell Screening and Imaging The transcript produced from this

The transcript produced from this gene has an unusually large 3' UTR which has not been completely sequenced

The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors

Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site

Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease

or type III hyperlipoproteinemia (HLP III)

Smad3 Polyclonal Antibody, 50ul[BT-AP14308] Cell Screening and Imaging The transcript produced from thisThe protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor beta and is thought to play a role in the regulation of