EGFR Polyclonal Antibody, 50ul[BT-AP15381] sgRNA Oligos PHLDA2 (pleckstrin homology like domain

PHLDA2 (pleckstrin homology like domain family A member 2) is located in a cluster of imprinted genes on chromosome 11p15

Defects in this gene may be associated with severe combined immunodeficiency (SCID)

The 206 amino acid precursor of GPIb beta is synthesized from a 1

The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections

which is thought to interact with KAP1

EGFR Polyclonal Antibody, 50ul[BT-AP15381] sgRNA Oligos PHLDA2 (pleckstrin homology like domainThe protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.