Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Alternatively spliced variants encoding different

Alternatively spliced variants encoding different isoforms have been reported| but their biological validity has not been determined

DUF1220 copy number variations in human chromosomal region 1q21

This gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein-coupled seven-transmembrane domain ligand

Alternatively spliced transcript variants encoding distinct isoforms have been reported

is a dimer composed of disulfide-linked heavy and light chains

Dvl-2 Polyclonal Antibody, 100ul Monoclonal Antibody Preparation Alternatively spliced variants encoding differentDVL2 encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. DVL2 encodes a 90 kD protein that undergoes posttranslational phosphorylation to form a 95 kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved