CIS Polyclonal Antibody, 50ul Virus Packaging May act by blocking phosphorylation

May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit

The encoded gene product presumably interacts with YY1 protein

MMP12 may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD)

The encoded protein requires synaptonemal complex protein 3

In nucleus

CIS Polyclonal Antibody, 50ul Virus Packaging May act by blocking phosphorylationThe protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM CSF and EPO in hematopoietic cells.