KLK10 Rabbit Polyclonal Antibody, 20ul Custom RNA Oligos Krueppel-like factor 12 encoded by

Krueppel-like factor 12 encoded by KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter

The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule

It appears that the human GnRHR2 transcription occurs but the gene does not likely produce a functional multi-transmembrane protein

This subunit may compete with PSMC2 for binding to the HIV tat protein to regulate the interaction between the viral protein and the transcription complex

Mutations in this gene cause epidermolysis bullosa junctional Herlitz type

KLK10 Rabbit Polyclonal Antibody, 20ul Custom RNA Oligos Krueppel-like factor 12 encoded byKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers.