DVL1 Polyclonal Antibody, 100ul Cellular Function Assays The encoded protein plays a

The encoded protein plays a role in multiple aspects of mRNA maturation and is associated with several multiprotein complexes including the apoB RNA editing-complex and survival of motor neurons (SMN) complex

|enzyme regulation:Activated by phosphorylation on Thr-174 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39

which may inhibit chondrosarcoma cell proliferation and migration

GO annotations related to this gene include G-protein coupled receptor activity andtransmembrane signaling receptor activity

This protein is thought to play a significant role in the signal transduction of hematopoietic cells

DVL1 Polyclonal Antibody, 100ul Cellular Function Assays The encoded protein plays aDVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz Jampel syndrome and Charcot Marie Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these