DNAM-1 Polyclonal Antibody, 100ul[BT-AP02672] Cryopreservation Mutations affecting this gene are

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIGM3)

GPR32P1 (G Protein-Coupled Receptor 32

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

Enhances androgen receptor-mediated transcription

familial hypertrophic cardiomyopathy

DNAM-1 Polyclonal Antibody, 100ul[BT-AP02672] Cryopreservation Mutations affecting this gene areCD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig superfamily containing 2 Ig like domains of the V set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.