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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage probably playing a role in

SKU: 35113660564

4.4
USD141.00 USD169.00

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Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage probably playing a role inAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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Description

probably playing a role in regulating LPS-dependent monocyte responses

that is cleaved to yield two peptides

Mapped to a previously identified cluster of cadherin genes on chromosome 16q22

Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes

and is resistant to harsh chemicals

Phospho-AIRE-1 (S156) Polyclonal Antibody, 100ul Liquid Handling &Storage probably playing a role inAIRE encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The autoimmune regulator plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T cells in the thymus. Mutations in this gene cause the rare autosomal recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and

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