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HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis subunit:Forms an heterooligomeric complex with

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HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis subunit:Forms an heterooligomeric complex withEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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Description

subunit:Forms an heterooligomeric complex with RAB11FIP4

The beta subunit may assist in binding of the phospholipid substrate (Probable)

API5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation

An important paralog of this gene is GPRIN2

Mutations in this gene have been associated with left-right axis malformations| particularly in the heart and lungs

HRI Polyclonal Antibody, 50ul DNA Oligo Synthesis subunit:Forms an heterooligomeric complex withEukaryotic translation initiation factor 2 alpha kinase 1encoded by EIF2AK1 acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms have been found for this gene.

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