JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates in a cluster with two

in a cluster with two closely related genes which encode similar proteins

The encoded protein interacts with CD3-zeta (CD247)

The protein localizes to membrane protrusions and is often expressed on adult stem cells

The product of this gene has the lowest sensitivity for these antagonists

Involved in the recruitment of beta-arrestin 2 ARRB2 at the plasma membrane in epithelial cells

JAK3(Phospho Tyr785) Polyclonal Antibody, 50ul Deep Well Plates in a cluster with twoThe protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).