DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments Guanine nucleotide exchange factor (GEF)

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B

invasion and metastasis of cancer cells

It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon

elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain

Expressed in atopic dermatitis| allergic contact dermatitis skin| and psoriasis| in both the eptdermis and dermis

DNA pol beta (Acetyl Lys72) Rabbit Polyclonal Antibody, 20ul DNA Fragments Guanine nucleotide exchange factor (GEF)Catalytic activity: Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). cofactor: Binds 2 magnesium ions per subunit. Residues 239 252 form a flexible loop which appears to affect the polymerase fidelity. Repair polymerase. Conducts "gap filling" DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases. Has a 5' deoxyribose 5 phosphate lyase (dRP lyase) activity. PTM: Methylation by