TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification The gene product is thought

The gene product is thought to be involved in several processes including regulation of the ARF/p53 pathway

cell signaling survival

The cyclin dependent kinase inhibitor 1C is a tight-binding

Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE)

Several alternatively spliced transcript variants encoding four distinct isoforms have been reported

TNF-IP 8 Polyclonal Antibody, 50ul DNA/RNA Isolation & Purification The gene product is thoughtTNFAIP8 (TNF Alpha Induced Protein 8) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include cysteine type endopeptidase inhibitor activity involved in apoptotic process. An important paralog of this gene is TNFAIP8L2. Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF mediated apoptosis by inhibiting caspase 8 activity but not the processing of procaspase 8,