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Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos The protein encoded by this

SKU: 36438152368

4.1
PLN123.75 PLN173.75

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Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos The protein encoded by thisApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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Description

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration

It is one of the components of a multiprotein complex required for exocytosis

Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing

calcium and phospholipid

The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database

Ref-1 Polyclonal Antibody, 100ul[BT-AP07734] Modified Oligos The protein encoded by thisApurinic apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. APEX1 encodes the major AP endonuclease in human cells.

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