Tensin-1 Polyclonal Antibody, 50ul Peptide Modification and serves as a mediating

and serves as a mediating factor for Ca (2+)- dependent inhibition of smooth muscle contraction

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Overexpression of this gene has been observed in some cancer cells

This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

studies of a similar gene in mice have shown that this gene may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis

Tensin-1 Polyclonal Antibody, 50ul Peptide Modification and serves as a mediatingThe protein encoded by TNS1 (tensin 1)localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. Alternative splicing results in multiple transcript variants encoding different isoforms.