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NCAM-L1 Polyclonal Antibody, 20ul[BT-AP05800] Vortex Mixer Mutations in this gene are

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NCAM-L1 Polyclonal Antibody, 20ul[BT-AP05800] Vortex Mixer Mutations in this gene areNeural cell adhesion molecule L1 encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.

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Description

Mutations in this gene are associated with acromesomelic dysplasia

Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and protein kinase activity

which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16 (INK4a)

These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana

CLK1 encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases

NCAM-L1 Polyclonal Antibody, 20ul[BT-AP05800] Vortex Mixer Mutations in this gene areNeural cell adhesion molecule L1 encoded by L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin like domains and fibronectin like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation.

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