NIPA(Phospho Ser354) Polyclonal Antibody, 50ul Bottles involved in retrograde transport of

involved in retrograde transport of proteins from endosomes to the trans-Golgi network

The phosphorylation of the complex by CDC2 kinase reduces the helicase activity

ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis

it mediates monoubiquitination of histone H2A 'Lys-119'

Mutations in this gene can cause early-onset axonal neuropathy

NIPA(Phospho Ser354) Polyclonal Antibody, 50ul Bottles involved in retrograde transport ofThis gene encodes an F box containing protein that is a component of an SCF type E3 ubiquitin ligase complex that regulates the onset of cell division. The G2 M transition in the cell cycle requires the interaction of the proteins cyclin B1 and cyclin dependent kinase 1. The activated ubiquitin ligase complex targets the protein cyclin B1 for degradation, preventing this transition to mitosis.