DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02654] Protein Research UBE3B (ubiquitin protein ligase E3B)

UBE3B (ubiquitin protein ligase E3B) encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates

This protein promotes apoptosis by interacting with the apoptotic inhibitors BCL-2 and BCL-X(L) via its BH3 domain

This putative nuclear transcription factor most likely functions in regulating the response to growth factors

not all variants give rise to a functional enzyme

Small G proteins| such as GTPBP10| act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis| nuclear transport| membrane trafficking| and signal transduction (Hirano et al

DNA Ligase IV Polyclonal Antibody, 100ul[BT-AP02654] Protein Research UBE3B (ubiquitin protein ligase E3B)DNA ligase 4 encoded by LIG4 is a DNA ligase that joins single strand breaks in a double stranded polydeoxynucleotide in an ATP dependent reaction. This protein is essential for V(D)J recombination and DNA double strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA dependent protein kinase (DNA PK). Both XRCC4 and